Rotation thromboelastometry velocity curve predicts blood loss during liver transplantation

Rotation thromboelastometry detects thrombocytopenia and hypofibrinogenaemia during orthotopic liver transplantation.

BACKGROUND Orthotopic liver transplantation can be associated with haemorrhage, particularly in patients with severe liver dysfunction. We assessed the value of rotation thromboelastometry (ROTEM) to monitor coagulation in the operating theatre, its correlation with routine laboratory findings, and its ability to guide platelet (Plt) and fibrinogen (Fg) transfusion. METHODS Twenty-three patie...

Physiology, prevention, and treatment of blood loss during liver transplantation

Excessive intraoperative blood loss independently predicts recurrence of hepatocellular carcinoma after liver transplantation

BACKGROUND Several studies have investigated the effect of intraoperative blood loss (IBL) on recurrence of tumors. However, the independent effect of IBL on oncological outcome after liver transplantation (LT) for hepatocellular carcinoma (HCC) is unclear. METHODS A total of 479 patients who underwent LT for HCC from January 2001 to December 2012 at our institution were enrolled in this retr...

Blood loss, predictors of bleeding, transfusion practice and strategies of blood cell salvaging during liver transplantation.

Blood loss during liver transplantation (OLTx) is a common consequence of pre-existing abnormalities of the hemostatic system, portal hypertension with multiple collateral vessels, portal vein thrombosis, previous abdominal surgery, splenomegaly, and poor "functional" recovery of the new liver. The intrinsic coagulopathic features of end stage cirrhosis along with surgical technical difficultie...

An assessment of thromboelastometry to monitor blood coagulation and guide transfusion support in liver transplantation.

BACKGROUND Rotation thromboelastometry (TEM) has been proposed as a convenient alternative to standard coagulation tests in guiding the treatment of coagulopathy during orthotopic liver transplantation (OLT). This study was aimed at assessing the value of TEM in monitoring blood coagulation and guide transfusion support in OLT. STUDY DESIGN AND METHODS Standard coagulation and TEM (EXTEM and ...